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By week 68, participants who took semaglutide lost an average of 15.1% of their body weight, compared to 2.4% in the placebo group

MOTS-C sits at the intersection of mitochondrial signaling, metabolism, and longevity

Kang R, et al

The GIP receptor activation facilitates glucose-dependent insulin release and plays a critical role in lipid metabolism, helping reduce fat deposition and improve overall energy balance

It works by targeting the messenger RNA of a protein that inhibits the clearance of triglycerides from the blood

Altered Fat Distribution: The dip in oestrogen causes fat to accumulate more in the upper part of the body, particularly around organs and the waistline