glp 1 itchy scalp One of the most common concerns I'm seeing in patients taking GLP-1 medications is hair loss. For some, it shows up as increased shedding; for others, it can be more dramatic with The Link Between GLP-1 Drugs

Approaches to improvements in efficacy primarily target additional gut hormones via dual- and tri-agonists, and if Mounjaro provides any indication, dual- and tri-agonists may not be likely to enhance tolerability

Austin Diabetes Res

Farxiga/Forxiga is not currently approved for weight loss as a standalone indication in non-diabetics, but the evidence is accumulating: Currently, if weight loss is the primary goal in a non-diabetic patient, GLP-1 agonists (semaglutide/Ozempic, tirzepatide/Mounjaro) produce substantially greater weight loss (1015% vs 24%)

At the same time, the median primary care visit is just 15.7 minutes, and most clinics do not offer weight care support, like nutritional counseling or support groups, to increase the chances of long-term success

Reduction of a trisulfide derivative of glutathione by glutathione reductase [PMID: 8060317] Laboratory literature summary: Reduction of a trisulfide derivative of glutathione by glutathione reductase

GLP-1 meds could offer a new way to help these patients