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BOX 7-1 Lesion Characteristics in Nails That Should Raise a Red Flag Location: Single digit, thumb, or great toe nails Appearance: Fast growth, longitudinal melanonychia, band width more than 3-5 mm Hutchinsons Sign: Periungual pigmentation of skin Nail Dystrophy: Notch in free distal nail margin, surface irregularity, oozing, or bleeding lesion similar to ingrown nail Melanonychia striata Brown longitudinal stria (plural is striae) that occurs in the nail is called melanonychia striata

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Compounded semaglutide is still a subcutaneous injection, but is handled using syringes instead of spring-loaded devices

This shows that while most people tolerate the medication, some stop due to side effects

Safety Considerations and Who Should Proceed with Caution Semaglutide is generally safe in hypothyroid patients, but certain conditions warrant extra vigilance