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The molecular core of this pathway, elucidated over the last decade, consists of RCAR/PYR1/PYL receptors, PP2C phosphatases, and SnRK2 kinases (Fujii et al

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observed that esaxerenone, a nonsteroidal selective compound, effectively decreased the expression of MCP-1 and inhibited the infiltration of inflammatory cells in DKD by suppressing ROS levels (212)

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