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Description

We outline new mechanistic concepts, future therapeutic opportunities, potential for differentiation from currently available medicines and areas of uncertainty requiring additional investigation

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Natural GLP-1 produces more modest, meal-related effects that are part of normal metabolic regulation

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Designed as a weekly under-the-skin injection, pemvidutide is a dual agonist of the GLP-1 and glucagon receptorsa targeting profile that Arbet-Engels said could set the drug apart in the alcohol use disorder (AUD) arena

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Ozempic is a single receptor agonist targeting only GLP-1

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It is widely accepted that multiple factors, including genetics and environment, contribute to the pathological development of psoriasis, but its etiology is complex and poorly understood [2]

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